A very cool and well-executed concept for an alternate Madness timeline. Mixes the refined nature of modern madness with its weight and kills with the iconic scenes of Depredation. I feel like the intro part with "the victims" and "the protagonist", while cool, isn't quite up to par with the iconic original, simply doesn't pack as much of a punch and the beginning was kinda weirdly animated, but I guess that's cause you didn't have time.
The kills were simply stellar, felt like a mix between Depredation-era fast, crazy fights and the knife-throwing, environment manipulating choreography of the earlier and later installments. I enjoyed the several melee clashes. The one with Jebus was especially exciting, as it lasted longer than the original and kept the suspense up the entire time with each side having to use their own fighting style and exploit their opponent's weaknesses. Tricky was a little less chaotic than the original for similar reasons to the intro being less exciting, just not enough over-the-top. However, that was okay, as he was still sold as really powerful, winning in the end. Hank was just able to make it out with help that didn't allow Tricky to get close.
This further developed Sanford, Deimos and 2bdamned as useful characters and connected them to Hank, whereas in the original series it's not very clear who they were and what they were doing. They just got dropped into the story, which is fine, as it was a story that evolved as time went on. I really appreciate you using these existing characters and finding a way to involve them in your version of the timeline instead of just copying depredation 1:1. You even included the Auditor and gave him an awesome theme. The updated and expanded sprites, weapons and scenery were gorgeous, and I love getting to see the city as a setting, as I don't recall ever seeing Hank put into one. The music remixes and sounds, fit the mood well and complemented the action. So great job to the people who made all these things and good job to you for picking them out.
Keep it up, I'd love to see more from you!